Stax mAx clarifes monoclonal antibody mobile cultures without having centrifugation or approach additives.
Pall Corporation is introducing the Stax mAx clarification system for the economic clarification of monoclonal antibody mobile cultures without having centrifugation or approach additives.
The solitary-use harvesting system functions a 4-layer notion, and has been optimized to preserve functionality as mobile density and viability alter to lessen the effects of approach variability concerning batches. Media configurations are obtainable in lots of formats to scale straight from bench-leading testing up to substantial-scale medical generation.
Finer grades
The pre-chosen 4-layer, 2 stage system functions sequentially finer grades to clear away aggregates, complete cells and mobile debris. Built to keep a compact footprint throughout a wide variety of feed streams (with mobile densities of up 35 x 106 cells/mL, and feed turbidities of up to about 3,000 NTU), the Stax mAx clarification system is scalable to aid 1,000 to 2,000 L mobile tradition volumes.
“As mobile densities improve, need has grown for much less tough, a lot more affordable, both footprint and price tag-sensible, clarification alternatives,” reported Mario Philips, vice president and basic supervisor of Pall Lifetime Sciences. “The Stax mAx clarification system was born from Pall’s legacy toughness in filtration, and leverages our tested Stax solitary-use capsule technique.
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